Sohrab Sadeghi, Masoud Hatefi, Aryoobarzan Rahmatian, Hassan Reza Mohammadi


Background: Hypertension is the most common cardiovascular disease that often causes stroke. The objectives of this study were, to evaluate the effects of level of consciousness, volume of hematoma, time interval between diagnosis and surgery and systolic blood pressure with mortality due to hypertensive cerebellar hemorrhage.

Materials & Methods: In this descriptive study, all patients who underwent surgery rom 1st January 2021 to 31st December 2021 due to cerebellar HTN hemorrhage in Imam Khomeini Hospital were investigated. After performing neurological examinations and determining the level of consciousness using the GCS criteria in all patients, brain CT-scan was performed. The indication for surgery was determined based on clinical examination and CT findings. The demographic and research variables were noted on preformed proforma. Data analysis was carried out using the descriptive in SPSS ver. 16.

Results: Total 25 patients were included in this study, in which 16 were female and 23 were older than 50 years age. Regarding the disease outcome, death occurred in 1 man and 10 women and similarly death occurred in 1 patient under 50 years of age, and 10 in patients over 50 years old. There was no relationship between M (SD) of systolic blood pressure and hematoma volume with mortality (P>0.05), but the mortality rate was higher in patients with longer diagnosis-to-surgery interval and those with a lower level of consciousness (p-value 0.001).

Conclusion: Patients with cerebellar hematoma should be operated early, as delay can lead to increased mortality.


Hypertension; Outcomes; Hypertension cerebellar.

Full Text:



Ramakrishnan S, Zachariah G, Gupta K, Rao JS, Mohanan P. Prevalence of hypertension among Indian adults: results from the great India blood pressure survey. Indian heart journal 2019;71(4):309-313. https://doi.org/10.1016/j.ihj.2019.09.012

Izadirad H, Masoudi GR, Zareban I. The Effect of Educational Program Based on BASNEF Model on Women's Blood Pressure with Hypertension. Journal of Torbat Heydariyeh University of Medical Sciences 2013;1(2):22-31.

Murray CJ, Lopez AD. Measuring the global burden of disease. New England Journal of Medicine 2013;369(5):448-457. https://doi.org/10.1056/NEJMra1201534

Mills KT, Bundy JD, Kelly TN, Reed JE, Kearney PM, Reynolds K, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation 2016;134(6):441-450. https://doi.org/10.1161/CIRCULATIONAHA.115.018912

Burnier M, Egan BM. Adherence in hypertension: a review of prevalence, risk factors, impact, and management. Circulation research 2019, 124(7):1124-1140. https://doi.org/10.1161/CIRCRESAHA.118.313220

Woodward M, Barzi F, Martiniuk A, Fang X, Gu D, Imai Y, et all. Cohort profile: the asia pacific cohort studies collaboration. International journal of epidemiology 2006;35(6):1412-1416. https://doi.org/10.1093/ije/dyl222

Mirzaei M, Moayedallaie S, Jabbari L, Mohammadi M. Prevalence of Hypertension in Iran 1980-2012: A Systematic Review. J Tehran Heart Cent 2016;11(4):159-167.

Kishore J, Gupta N, Kohli C, Kumar N. Prevalence of Hypertension and Determination of Its Risk Factors in Rural Delhi. International Journal of Hypertension 2016;2016:7962595. https://doi.org/10.1155/2016/7962595

Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, et all. Heart disease and stroke statistics- a report from the American Heart Association. Circulation 2018;137(12):e67-e492. https://doi.org/10.1161/CIR.0000000000000573

Ma SM, John J. Assess the prevalence of hypertension and knowledge regarding the prevention of stroke. Asian J Pharm Clin Res 2017;10(8):177-180. https://doi.org/10.22159/ajpcr.2017.v10i8.18558

Lakičević G, Arnautović K, Mužević D, Chesney T. Cerebellar glioblastoma multiforme presenting as hypertensive cerebellar hemorrhage: case report. Journal of Neurological Surgery Reports 2014;75(01):e117-e121. https://doi.org/10.1055/s-0034-1376198

Valenzuela PL, Carrera-Bastos P, Gálvez BG, Ruiz-Hurtado G, Ordovas JM, Ruilope LM, et al A. Lifestyle interventions for the prevention and treatment of hypertension. Nature Reviews Cardiology 2021;18(4):251-275. https://doi.org/10.1038/s41569-020-00437-9

Diaz-Gutierrez J, Ruiz-Estigarribia L, Bes-Rastrollo M, Ruiz-Canela M, Martin-Moreno JM, Martinez-Gonzalez MA. The role of lifestyle behaviour on the risk of hypertension in the SUN cohort: the hypertension preventive score. Preventive medicine 2019;123:171-178. https://doi.org/10.1016/j.ypmed.2019.03.026

Ahmadabadi S, Alavian F, Sedaghati P. Effectiveness of Motor Interventions in Improving the Motor Abilities of Post-stroke Patients: A Systematic Review. The Scientific Journal of Rehabilitation Medicine 2022;10(6):1140-1155. https://doi.org/10.32598/SJRM.10.6.2

Zhao J, Zhou C. The protective and hemodynamic effects of dexmedetomidine on hypertensive cerebral hemorrhage patients in the perioperative period. Experimental and Therapeutic Medicine 2016;12(5):2903-2908. https://doi.org/10.3892/etm.2016.3711

Zhao XH, Zhang SZ, Feng J, Li ZZ, Ma ZL. Efficacy of neuroendoscopic surgery versus craniotomy for supratentorial hypertensive intracerebral hemorrhage: A meta-analysis of randomized controlled trials. Brain and Behavior 2019, 9(12): e01471. https://doi.org/10.1002/brb3.1471

Mirsen T. Acute Treatment of Hypertensive Intracerebral Hemorrhage. Current Treatment Options in Neurology 2010;12(6):504-517. https://doi.org/10.1007/s11940-010-0096-3

Wang GQ, Li SQ, Huang YH, Zhang WW, Ruan WW, Qin JZ, et al. Can minimally invasively puncture and drainage for hypertensive spontaneous Basal Ganglia intracerebral hemorrhage improve patient outcome: a prospective non-randomized comparative study. Military Medical Research 2014;1(1):1-12. https://doi.org/10.1186/2054-9369-1-10

Yamamoto T, Nakao Y, Mori K, Maeda M. Endoscopic hematoma evacuation for hypertensive cerebellar hemorrhage. min-Minimally Invasive Neurosurgery 2006;49(03):173-178. https://doi.org/10.1055/s-2006-944242

Wang W, Zhou N, Wang C. Minimally invasive surgery for patients with hypertensive intracerebral hemorrhage with large hematoma volume: a retrospective study. World Neurosurgery 2017;105:348-358. https://doi.org/10.1016/j.wneu.2017.05.158

Li Z, Luo Y, Jin M, Chen D, Shi P, Xu X. Clinical therapeutic effect of different surgical approaches on the hypertensive intracerebral. J Dalian Med Univ 2012;34(1):60-63.

Yi F, Jianqing H, Bin L, Likun Y, Yuhai W. Endoscope-assisted keyhole technique for hypertensive cerebral hemorrhage in elderly patients: a randomized controlled study in 184 patients. Turkish Neurosurgery 2016;26(1).

Lin SW, Hu JQ, Yu SY. The minimally invasive surgery on hypertensive cerebral hemorrhage. CHINESE JOURNAL OF NEUROLOGY 2004;37(4):307-310.

Feng Y, He J, Liu B, Yang L, Wang Y. Endoscope-Assisted Keyhole Technique for Hypertensive Cerebral Hemorrhage in Elderly Patients: A Randomized Controlled Study in 184 Patients. Turk Neurosurg 2016;26(1):84-89. https://doi.org/10.5137/1019-5149.JTN.12669-14.0

Tang Y, Yin F, Fu D, Gao X, Lv Z, Li X. Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis. BMC Neurology 2018;18(1):136. https://doi.org/10.1186/s12883-018-1138-9

Hou D, Lu Y, Wu D, Tang Y, Dong Q. Minimally Invasive Surgery in Patients with Intracerebral Hemorrhage: A Meta-Analysis of Randomized Controlled Trials. Frontiers in Neurology 2022;12. https://doi.org/10.3389/fneur.2021.789757

Komlakh K, Karbasfrushan A. The effect of Pregabalin on the pain status of patients with disc and spinal surgeries: A systematic review of drug therapy. EURASIAN CHEMICAL COMMUNICATIONS 2022;4(11):1147-55.

Tarjoman A, Borji M, Safari S, Otaghi M. Investigating the effects of adaptive stability model on headache of patients with migraine. Archives of Neuroscience 2019;6(1).29. https://doi.org/10.5812/ans.81492

Vasigh A, Tarjoman A, Soltani B, Borji M. The relationship between mindfulness and self-compassion with perceived pain in migraine patients in Ilam, 2018. Archives of Neuroscience. 2019;6(3). https://doi.org/10.5812/ans.91623

Tahmasbi F, Madani Neishaboori A, Mardani M, Toloui A, Komlakh K, Azizi Y, Yousefifard M. Efficacy of polyarginine peptides in the treatment of stroke: A systematic review and meta-analysis. Brain and Behavior 2023 Jan;13(1):e2858. https://doi.org/10.1002/brb3.2858

Darabi B, Shokri M, Bastani E. INVESTIGATING SPIROMETRY INDICES IN CHILDREN WITH ASTHMA. Gomal Journal of Medical Sciences 2023 Oct 2;21(3):145. https://doi.org/10.46903/gjms/21.03.1289

Bastani E, Shokri F. Incidence Trend of Lung Cancer in Iran: A Systematic Review and Meta-analysis. Int J Cancer Manag. 2023;16(1):e135020. https://doi.org/10.5812/ijcm-135020.

Fazelipour S, Adhami Moghadam F, Davudi P, Tootian Z, Assadi F. Histometrical study of ovarian follicles of immature mice treated with methylphenidate. Journal of Veterinary Research, 2015;70(3):301-7. https://doi.org/10.22059/jvr.2015.55274

DOI: https://doi.org/10.46903/gjms/21.04.1316


  • There are currently no refbacks.

Copyright (c) 2023. Sohrab Sadeghi, Masoud Hatefi, Aryoobarzan Rahmatian, Hassan Reza Mohammadi

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Gomal Medical College, Daraban Road, Dera Ismail Khan, Pakistan

ISSN: 1819-7973, e-ISSN: 1997-2067

Website: https://www.gmcdikhan.edu.pk

Phone: +92-966-747373

Scimago Journal & Country Rank