FREQUENCY OF COMMON CAUSATIVE ORGANISM AND THEIR ANTIBIOTIC SENSITIVITY IN DIABETIC FOOT ULCER PATIENTS PRESENTED AT GULAB DEVI TEACHING HOSPITAL

Usman Ali Rahman; Muhammad Adil Iftikhar; mohammad zia ul Miraj; Khalil Ahmed; Maliha Javaid Butt; Iftikhar Ahmed

doi:10.46903/gjms/21.04.1396

FREQUENCY OF COMMON CAUSATIVE ORGANISM AND THEIR ANTIBIOTIC SENSITIVITY IN DIABETIC FOOT ULCER PATIENTS PRESENTED AT GULAB DEVI TEACHING HOSPITAL

Usman Ali Rahman, Muhammad Adil Iftikhar, mohammad zia ul Miraj, Khalil Ahmed, Maliha Javaid Butt, Iftikhar Ahmed

Abstract

Background: Diabetic foot ulcers are the most common ulcer presentation in surgical and medical units. The drug resistance against antibiotics is continuously increasing due to overuse of antibiotics by general practitioners. The objective of this study was to determine organisms involved in diabetic foot ulcers and their susceptibility to antibiotics for use as empirical therapy.

Materials & Methods: It was a cross sectional study held at Surgical Department of Gulab Devi Teaching hospital from January 2021 to December 2021. A total of 130 patients were recruited who presented with diabetic foot wounds and underwent surgical debridement. After debridement tissue and wound discharge was sent for culture and sensitivity. Data was analyzed by SPSS 24.0. Quantitative data was summarized as mean, median, mode and standard deviation while qualitative data was summarized as frequency and in tables.

Results: Total 130 patients were included in this study. The mean age of these patients was 58.3 ±11.0 years. Maximum frequency of patients (45.7%) was found in age group of 52-67 years. The mean duration of ulcer on foot was 15.1 ±0.9 days. Among 119 culture positive patients pseudomonas was the most frequent organism followed by E.coli, Gram negative rods and Klebsiella. Highest frequency of antimicrobial sensitivity was seen with Meropenem (46.1%), followed by Colistin (34.6%), Imipenem (31.5%) Linezolid (27.7%).

Conclusion: The study’s findings are that diabetic foot ulcers are most frequently polymicrobial and some antibiotics like Meropenem, Colistin Imipenem, Linezolid, Ciprofloxacin, Levofloxacin, Cefipime & Tiecoplanan can be used as drug of choice for management of diabetic foot ulcers.

Keywords

Diabetic foot ulcers; Microorganisms; Empirical therapy.

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DOI: https://doi.org/10.46903/gjms/21.04.1396