PREVALENCE OF DEPRESSION IN PATIENTS OF FACIAL HIRSUTISM IN OUTPATIENT DEPARTMENT OF DERMATOLOGY, KHYBER TEACHING HOSPITAL, PESHAWAR: A CROSS-SECTIONAL STUDY
Abstract
Materials & Methods: This cross-sectional study was conducted in the Department of Dermatology, Khyber Teaching Hospital, Peshawar from April 10, 2021, to October 10, 2021. A total of 127 women with facial hirsutism were included. The sample size was calculated using the, “WHO sample size software” with a 95% confidence interval, 8% margin of error and prevalence of depression to be 30% in women with hirsutism. Participants were selected through consecutive non-probability sampling. Depression was assessed using the Hamilton Depression Rating Scale (HDRS). Ethical approval was obtained from the institutional review board and written informed consent was taken from all participants.
Results: Participants in the study ranged in age from 15 to 40 years; their mean age was 26.291 years, and the average length of their complaints was 5.480 months. Depression was noted in 37% of hirsutism patients. In this study, 19.7% of patients were unmarried, 80.3% of patients were married. Also, as the duration of the complaint lengthened, as indicated by our findings, women got more concerned about hirsutism.
Conclusion: We conclude from our study that hirsutism has a significant impact on the mental status of the patients which leads to depression. Trainee medical officer, psychiatry department
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Matheson E, Bain J. Hirsutism in women. Am Fam Physician. 2019;100(3):168-75.
Van Zuuren EJ, Fedorowicz Z, Carter B, Pandis N. Interventions for hirsutism (excluding laser and photoepilation therapy alone). Cochrane Database Syst Rev. 2015;(4):CD010334. https://doi.org/10.1002/14651858.CD010334.pub2
Scaruffi E, Gambineri A, Cattaneo S, Turra J, Vettor R, Mioni R. Personality and psychiatric disorders in women affected by polycystic ovary syndrome. Front Endocrinol (Lausanne). 2014;5:185. https://doi.org/10.3389/fendo.2014.00185
Ormel J, Kessler RC, Schoevers R. Depression: more treatment but no drop in prevalence: how effective is treatment? and can we do better? Curr Opin Psychiatry. 2019;32(4):348-54. https://doi.org/10.1097/YCO.0000000000000505
Pham TH, Gardier AM. Fast-acting antidepressant activity of ketamine: highlights on brain serotonin, glutamate, and GABA neurotransmission in preclinical studies. Pharmacol Ther. 2019;199:58-90. https://doi.org/10.1016/j.pharmthera.2019.02.017
Namkung H, Lee BJ, Sawa A. Causal inference on pathophysiological mediators in psychiatry. Cold Spring Harb Symp Quant Biol. 2018;83:17-23. https://doi.org/10.1101/sqb.2018.83.037655
Mangla K, Hoffman MC, Trumpff C, O'Grady S, Monk C. Maternal self-harm deaths: an unrecognized and preventable outcome. Am J Obstet Gynecol. 2019;221(4):295-303. https://doi.org/10.1016/j.ajog.2019.02.056
Shelton RC. Serotonin and norepinephrine reuptake inhibitors. Handb Exp Pharmacol. 2019;250:145-80. https://doi.org/10.1007/164_2018_164
Tanner J, Zeffiro T, Wyss D, Perron N, Rufer M, Mueller-Pfeiffer C. Psychiatric symptom profiles predict functional impairment. Front Psychiatry. 2019;10:37. https://doi.org/10.3389/fpsyt.2019.00037
Lipton MG, Sherr L, Elford J, Rustin MH, Clayton WJ. Women living with facial hair: the psychological and behavioral burden. J Psychosom Res. 2006;61(2):161-8. https://doi.org/10.1016/j.jpsychores.2006.01.016
Naheed A, Hayat AA, Ain Q, Razzaque B, Fatima S, Dar N. Psychological morbidity in patients with idiopathic hirsutism presenting for laser treatment at a tertiary care hospital. J Rawalpindi Med Coll. 2021;25(3):345-50. https://doi.org/10.37939/jrmc.v25i3.1547
Chabra S, Gautam RK, Kulusshreshta B, Prasad A, Sharma N. Hirsutism: a clinico-investigative study. Int J Trichol. 2012;4:246-50. https://doi.org/10.4103/0974-7753.111204
Mahajan VK, Chauhan PS, Chandel M, Mehta KS, Singh VK, Sharma A, et al. Clinico-investigative attributes of 122 patients with hirsutism: A 5-year retrospective study from India. Int J Womens Dermatol. 2021;7(3):237-42. https://doi.org/10.1016/j.ijwd.2020.11.007
Baig T, Aman S, Nadeem M, Kazmi AH. Quality of life in patients of hirsutism. J Pak Assoc Dermatol. 2014;24:217-23.
Pate C. The story plot of living the embarrassment of hirsutism. Arch Psychiatr Nurs. 2013;27:156-7. https://doi.org/10.1016/j.apnu.2013.02.003
Hodeeb YM, Al Dinary AM, Hassan HM, Samy DA. Hirsutism and health-related quality of life. Mod Chem Appl. 2015;2:170. https://doi.org/10.4172/2329-6798.1000170
Ekback MP, Lindberg M, Benzein E, Arestedt K. Health-related quality of life, depression and anxiety correlate with the degree of hirsutism. Dermatology. 2013;227:278-84. https://doi.org/10.1159/000355356
Ilyas U, Rafique S. Social anxiety and psychological distress among polycystic ovarian syndrome patients in Pakistan. J Pak Med Assoc. 2024;74(4):684-8. https://doi.org/10.47391/JPMA.9471
Nazar W, Minhas AH, Shafi S, Batool M, Sarwar A, Ibrar M. Psychosocial impact of hirsutism in female patients attending dermatology OPD of CMH Kharian. Indus J Biosci Res. 2024;3(1). https://doi.org/10.70749/ijbr.v3i1.541
Martin KA, Anderson RR, Chang RJ, Ehrmann DA, Lobo RA, Murad MH, et al. Evaluation and treatment of hirsutism in premenopausal women: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2018;103(4):1233-57. https://doi.org/10.1210/jc.2018-00241
Kiran KC, Gupta A, Gupta M. The effect of hirsutism on the quality of life of Indian women. Int J Res Dermatol. 2018;4(1):[page numbers]. https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20180142
Ghosh A, Ghosh A, Islam SKM, Oza R. Psychological impact on the quality-of-life in patients of psoriasis vulgaris: A systemic review. Asian J Med Sci. 2024;15(5):260-8. https://doi.org/10.71152/ajms.v15i5.555
Chernyshov PV, Sampogna F, Raimondi G, Gieler U, Tomas-Aragones L, Dalgard FJ, et al. Development of the acne-specific quality of life questionnaire: Quality of Life Relevance-Acne (QoL-Re-Acne). JAAD Int. 2024. https://doi.org/10.1016/j.jdin.2024.02.003
Bibi S, Malik SE, Zeb S, Javed J. Modified Ferriman-Gallwey Score and hirsutism among normal healthy female population. Pak J Med Sci. 2024;40(3):332-6. https://doi.org/10.12669/pjms.40.3.8138
DOI: https://doi.org/10.46903/gjms/23.1.Special.1143
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