LEFT ATRIUM VOLUME INDEX AND DIASTOLIC DYSFUNCTION IN NORMOTENSIVE DIABETIC PATIENTS

Hamid Naif; Zahraa Ch. Hameed

doi:10.46903/gjms/23.1.Special.1676

LEFT ATRIUM VOLUME INDEX AND DIASTOLIC DYSFUNCTION IN NORMOTENSIVE DIABETIC PATIENTS

Hamid Naif, Zahraa Ch. Hameed

Abstract

Background: Diabetes mellitus causes hyperglycemia owing to insulin secretion, action, or both. This study evaluates left ventricular diastolic function in diabetics without cardiac symptoms who have left ventricle impairment early and late. To link LVDD to Type 1 and Type 2 diabetes duration, HbA 1c, fasting sugar, and smoking.

Materials & Methods: This prospective cross-sectional study was conducted at Marjan Teaching Hospital and the Diabetic Endocrine Center in Babylon province from December 2019 to July 2022. It included 104 referred patients. Demographic data such as age, gender, blood pressure, height, weight, Body Surface Area, disease duration. 5 ml of blood was collected from group for the purpose of measuring hematological parameters (fasting blood sugar (FBS), glycated hemoglobin (HbA1C)). Left Atrium volume index (LAVI), Time of Deceleration (DT), and Isovolumic relaxation time (IVRT) were collected by the trans-mitral Doppler. Inclusion criteria: Any patient with normotensive diabetic and Diastolic Dysfunction. Exclusion criteria was patients with blood pressure equal or above 140/90 on more than 3 readings.

Results: HbA1C levels varied from 6 to 15%. Among the patients, 72 had moderate to severe HbA1C levels, 27.9% had normal HbA1C, and 2.9% had mild HbA1C levels. The mean (LAVI) was 38. Normal LAVI was observed in 34.6% of patients, while 42.3% had Grade 1 LAVI, 16.3% had Grade 2, and 6.7% had Grade 3. Diastolic dysfunction was present in 42% of patients (Grade 1), with 16.3% having Grade 2 and 6.7% having Grade 3 DD. A negative correlation was found between gender, smoking, and (LVDD). Positive correlations were observed between age, HbA1C, disease duration, and LAVI with diabetes severity and DD grades.

Conclusion: Patients with higher HbA1C and longer diabetes duration had higher LAVI. Additionally, older diabetic patients exhibited more severe diastolic dysfunction.

Keywords

Diabetes Mellitus; Diastolic Dysfunction; FBS; HbA1C; LAVI; DT.

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References

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DOI: https://doi.org/10.46903/gjms/23.1.Special.1676