COMPARISON OF PERITONSILLAR INFILTRATION OF ADRENALINE VERSUS NORMAL SALINE IN CONTROLLING PER OPERATIVE HAEMORRHAGE DURING TONSILLECTOMY

Zainab Shahid; Saleh Khurshied; Ghazal Iftakhar; Imdad Ullah; Umera Iftikhar; Nawal Khurshid; Ahmed Hasan Ashfaq

doi:10.46903/gjms/23.1.Special.1712

COMPARISON OF PERITONSILLAR INFILTRATION OF ADRENALINE VERSUS NORMAL SALINE IN CONTROLLING PER OPERATIVE HAEMORRHAGE DURING TONSILLECTOMY

Zainab Shahid, Saleh Khurshied, Ghazal Iftakhar, Imdad Ullah, Umera Iftikhar, Nawal Khurshid, Ahmed Hasan Ashfaq

Abstract

Background: A popular, low-risk operation is tonsillectomy. It is among the ENT profession’s most traditional operations. Techniques for tonsillectomy have undergone continuous modification. Haemorrhage is the most frequent, albeit rare, serious, potentially fatal side effect following tonsillectomy, especially with the development of contemporary preventative methods. The aim of this study was to determine the effect of pre-incisional peritonsillar infiltration of adrenaline versus normal saline on per-operative blood loss during tonsillectomy.

Materials & Methods : This six-month, double-blind, randomized clinical trial was conducted in the department ENT at Benazir Bhutto Hospital in Rawalpindi from July 20, 2022, to January 19, 2023. The study included 60 individuals in all, ages 6 to 18, who met certain inclusion and exclusion requirements. To facilitate blinding, the operation room nurse prepared identical syringes containing 1:200,000 adrenaline solution and Normal Saline. The syringes were then coded. The study was conducted in a double-blind fashion, meaning that neither the surgeon nor the patient knew which medication had been administered on which side. The tonsil was removed using a snare and dissection technique. SPSS version 25 was used to enter the data. An independent sample t-test was applied to see whether there was a significant association.

Results: The patients’ mean age was 11.7±3.4 years. Out of total, 25 were female (41.7%) and 35 were male (58.3%). 33 patients (55%) had tonsils that were 1-2 on the Brodsky grading scale, while 27 patients (45%) had tonsils that were 3–4. In normal saline and adrenaline, the mean pre-operative blood loss was found to be 86.4±11.3 and 41.0±10.4, respectively. P value of less than 0.001 indicated a statistically significant difference between the two groups.

Conclusion: In conclusion, peritonsillar infiltration of adrenaline resulted in a significant decrease in intraoperative blood loss compared to the normal saline group. (p<0.001).

Keywords

Adrenaline; Haemorrhage; Infiltration; Per-operative; Saline; Tonsillectomy.

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DOI: https://doi.org/10.46903/gjms/23.1.Special.1712