PREVALENCE AND FACTORS IN DIABETIC RETINOPATHY IN OBESE FEMALES PRESENTING AT LADY READING HOSPITALS
Abstract
Background: Diabetic retinopathy (DR) is a disease that does not exhibit symptoms in the early stages, which makes early detection crucial. To prevent new cases of blindness caused by inadequate management, a systematic approach to DR screening and a follow-up care system are required. The aim of this study was to examine the prevalence of diabetic retinopathy (DR) and its related variables in patients with diabetes treated at Lady Reading Hospital in Peshawar between July 1, 2023, and June 30, 2024.
Materials & Methods: Patients in this descriptive cross-sectional study, who were diabetes patients between the ages of 30 and 60, were treated at Lady Reading Hospital in Peshawar. Patients with a diagnosis of either Type 1 or Type 2 diabetes mellitus, complete medical records, and the ability to give informed permission were the requirements for inclusion. Patients with insufficient medical data, individuals who were pregnant, patients with additional retinal illnesses, and patients who refused to give consent were all excluded. With an emphasis on demographics, comorbidities, lifestyle factors, and clinical data, data was gathered through structured interviews, physical examinations, and inspections of medical records. Examinations of the eyes verified the existence of DR. Using chi-square tests, logistic regression analysis, and descriptive statistics, SPSS software version 24.0 was used to analyze the data with sample size 121 patients.
Results: Patients with DR had a lower prevalence of cardiovascular illnesses (6%) compared to those without (51%), with a p-value of 0.001. Significant correlations were found between DR and high blood pressure (36.7% vs. 5.7%, p=0.002) and inflammation (42.4% vs. 7.9%, p=0.001). A strong correlation was seen between DR and higher parity (>2 children) (50% vs. 16.9%, p=0.006). Significant variables included being older (46–60 years, 52.9% vs. 30-45 years, 17.2%, p=0.003), married (55.5% vs. single, 0%, p=0.004), and a housewife (31.1% vs. employed, 5.6%, p=0.025). There was no significant correlation found between smoking status and p=0.283.
Conclusion: Inflammation, higher parity, age, married status, and homemaker status were all found to be significant risk factors for diabetic retinopathy in the study. In order to reduce the risk of DR, these findings emphasize the necessity of focused screening and management programs for at-risk populations. Reducing the prevalence of diabetes-related disorders (DR) in patients may need careful blood pressure control as well as managing inflammation.
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Sun H, Saeedi P, Karuranga S. IDF diabetes Atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract. 2021;183:109119. https://doi.org/10.1016/j.diabres.2021.109119
Zang P, Gao L, Hormel TT. DcardNet: diabetic retinopathy classification at multiple levels based on structural and angiographic optical coherence tomography. IEEE Trans Biomed Eng. 2021;68(6):1859–70. https://doi.org/10.1109/TBME.2020.3027231
Teo ZL, Tham YC, Yan Yu MC. Global prevalence of diabetic retinopathy and projection of burden through 2045: systematic review and meta-analysis. Ophthalmology. 2021;128(11):1580–91. https://doi.org/10.1016/j.ophtha.2021.04.027
Al-Rashdi FA, Al-Mawali A. Prevalence of diabetic retinopathy in Oman: a two-decade national study. Oman Med J. 2021;36(2):e238. https://doi.org/10.5001/omj.2021.57
Al-Mawali A, Al-Harrasi A, Jayapal SK. Prevalence and risk factors of diabetes in a large community-based study in the Sultanate of Oman: STEPS survey 2017. BMC Endocr Disord. 2021;21(1):56. https://doi.org/10.1186/s12902-020-00655-9
Pawar S, Parkar A, Menon S, Desai N, Namrata D, Dole K. Assessment of quality of life of the patients with diabetic retinopathy using national eye institute visual functioning questionnaire (VFQ-25). J Healthc Qual Res. 2021;36(4):225–30. https://doi.org/10.1016/j.jhqr.2021.02.004
Mohamed Z, Al-Natour M, Al Rahbi H. Prevalence of diabetic retinopathy among individuals with diabetes in Gulf Cooperation Council countries: a systematic review and meta-analysis. Oman Med J. 2024;39(1):e585. https://doi.org/10.5001/omj.2024.77
Narang S, Deswal J, Gupta N, Jinagal J, Sindhu M. To study the impact of diabetic retinopathy on quality of life in Indian diabetic patients. Indian J Ophthalmol. 2020;68(5):848. https://doi.org/10.4103/ijo.IJO_1553_19
Aguirre IR-M, Rodríguez-Fernández P, González-Santos J. Exploring the quality of life related to health and vision in a group of patients with diabetic retinopathy. Healthcare. 2022;10(1):142. https://doi.org/10.3390/healthcare10010142
Hsieh AR, Huang YC, Yang YF, Lin HJ, Lin JM, Chang YW. Lack of association of genetic variants for diabetic retinopathy in Taiwanese patients with diabetic nephropathy. BMJ Open Diabetes Res Care. 2020;8(1):e000727. https://doi.org/10.1136/bmjdrc-2019-000727
Barnstable CJ. Epigenetics and degenerative retinal diseases: prospects for new therapeutic approaches. Asia Pac J Ophthalmol. 2022;11(4):328–34. https://doi.org/10.1097/APO.0000000000000520
Wang FY, Kang EY, Liu CH, Ng CY, Shao SC, Lai EC. Diabetic patients with rosacea increase the risks of diabetic macular edema, dry eye disease, glaucoma, and cataract. Asia Pac J Ophthalmol. 2022;11(6):505–13. https://doi.org/10.1097/APO.0000000000000571
Hui VW, Szeto SK, Tang F, Yang D, Chen H, Lai TY. Optical coherence tomography classification systems for diabetic macular edema and their associations with visual outcome and treatment responses – an updated review. Asia Pac J Ophthalmol. 2022;11(3):247–57. https://doi.org/10.1097/APO.0000000000000468
Sorour OA, Levine ES, Baumal CR, Elnahry AG, Braun P. Persistent diabetic macular edema: definition, incidence, biomarkers, and treatment methods. Surv Ophthalmol. 2023;68(2):147–74. https://doi.org/10.1016/j.survophthal.2022.11.008
Bhatwadekar AD, Shughoury A, Belamkar A, Ciulla TA. Genetics of diabetic retinopathy, a leading cause of irreversible blindness in the industrialized world. Genes. 2021;12(8):1200. https://doi.org/10.3390/genes12081200
Haq Z, Yang D, Psaras C, Stewart JM. Sex-based analysis of potential inflammation-related protein biomarkers in the aqueous humor of patients with diabetes mellitus. Transl Vis Sci Technol. 2021;10(3):12. https://doi.org/10.1167/tvst.10.3.12
DOI: https://doi.org/10.46903/gjms/23.2.1721
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