Zahid Gul, Anwar Zeb Jan, Fahad Liaqat, Muhammad Safdar Qureshi


Background: The spectrum of pediatric uropathogens keeps on changing frequently, particularly in tertiary care settings catering a diverse patient population. The present study was conducted to determine the causative organisms and anti-microbial sensitivity pattern of uropathogens in children at Rehman Medical Institute Peshawar, Pakistan.
Material & Methods: This was a retrospective descriptive study from the patient records of 106 children aged 6 months to 14 years with confirmed diagnosis of urinary tract infection based on urine culture and sensitivity reports. The study was carried out from June 01 to July 15, 2013 and included data of children admitted to the Department of Pediatrics, Rehman Medical Institute, Peshawar, over a period of 6 years i.e. January 2007 to December 2012.
Results: The male to female ratio was 1:1.8 (34.9% males, 65.1% female). The common presenting symptoms were dysuria, flank pain, fever, restlessness due to pain and weakness. The most common isolated organism was E. coli (65.1%) followed by E. fecalis (20.8%). Regarding sensitivity pattern; Vancomycin, Amikacin, Nitrofurantoin and Impinime showed good sensitivity while Ampicillin and Ceftriaxone showed highest resistance.
Conclusion: The resistant pattern of uropathogens causing urinary tract infections to common antimicrobial agents is changing and it must be taken into consideration when selecting treatment strategies.


Urinary tract infections; Microbial sensitivity tests; Gram-Negative bacteria; Gram-Positive bacteria.

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