CYTOMORPHOLOGICAL PATTERN OF SUPERFICIAL LYMPHADENOPATHY

Mir Attaullah Khan, Walayat Shah, Shagufta Naser Pervez, Shafiullah Khan, Shah Jehan, Sadar Rahim

Abstract


Background: FNAC is considered as a reliable and inexpensive test for diagnosing lymphadenopathy cases with a high degree of accuracy. The objective of this study was to determine the cytomorphological pattern of superficial lymph node aspirates.
Material & Methods: This cross-sectional study was conducted in the Department of Pathology, Bannu Medical College, Bannu, Pakistan from October, 2012 to September, 2013. All patients with superficial lymphadenopathy were included in the study. Patients with a history of less than four weeks lymphadenopathy, having acute inflammatory process in the draining area or having lymphadenopathy due to known primary malignancy were excluded. The demographic variables were sex, age in years and age grouping. The research variables were site and cause of lymphadenopathy. Age grouping was; up to 15 years, 16-40 years and above 40 years.
Results: Out of 235 cases, there were 110(46.80%) males and 125(53.20%) females. The mean age of the sample was 35.00±13.50 (05-70) years. The frequency of age group up to 15 years was 82(34.90%), of 16-40 years was 50(21.27%) and of above 40 years was 103(43.83%). Site of lymphadenopathy were; left cervical lymph nodes in 105 (44.68%), right cervical lymph nodes in 60(25.53%), bilateral cervical lymph nodes in 11(4.68%), axillary lymph nodes in 30(12.76%), and other sites were involved in 29(12.35%) cases. The most cause of lymphadenopathy was chronic granulomatous lymphadenitis in 110 (46.8%).
Conclusion: Fine needle aspiration cytology is a good diagnostic tool in diagnosis of lymphadenopathy and will significantly enhance the institution of timely and appropriate treatment regimens.

Keywords


Fine needle aspiration; Cytology; Lymphadenitis; Reactive lymphoid hyperplasia; Lymphadenopathy; Tuberculous lymphadenopathy; Cytopathology; Lymphoproliferative Disorders

Full Text:

PDF

References


Akinde OR, Anunobi CC, Abudu EK, Daramola AO, Banjo AA, Abdulkareem FB, et al. Pattern of lymph node pathology in Lagos. Nig Q J Hosp Med 2011; 21:154-58.

Maula F, Iqbal Z, Anwar K, Said M, Khan J, Rehman H, et al. Histopathalogical pattern of lymph node biopsies taken in three teaching hospitals of Bannu (KPK). Pak J Chest Med 2012; 18:3-6.

Ahmed N, Israr S, Ashraf MS. Comparison of fine needle aspiration cytology (FNAC) and excision biopsy in the diagnosis of cervical lymphadenopathy. Pak J Surg 2009; 25:72-5.

Hibbert J. Metastatic neck disease. Otolaryngology 1997; 5: 1-18.

Olu-Eddo AN, Ohanaka CE. Superficial lymphadenopathy in Nigerian adults. J Pak Med Assoc 2006; 56:405-8.

Niedzielska G, Kotowski M, Niedzielski A, Dybiec E, Wieczorek P. Cervical lymphadenopathy in children-Incidence and diagnostic management. Int J Ped Otorhinol 2007; 71:51-6.

Munir MK, Shabbir I, Iqbal R, Khan SU, Syed ZA. Diagnosis of extra-pulmonary tuberculosis: conventional versus newer methods. Pak J Chest Med 2009; 15:11-4.

Ageep AK. Assessment of adult superficial lymphadenopathy in Red Sea State, Sudan. Int J Trop Dis Health 2012; 2:24-32.

Qadri SK, Hamdani NH, Shah P, Lone MI, Baba KM. Profile of lymphadenopathy in Kashmir valley: a cytological study. APJC 2012; 13:3621-5.

Ahmad I. Non-specific reactive hyperplasia of cervical lymph nodes: a follow-up. J Pak Med Assoc 1992; 37:237-8.

Ochicha O, Edino ST, Mohammed AZ, Umar AB, Atanda AT. Pathology of superficial lymph node biopsies in Kano, Northern Nigeria. Ann Afr Med 2007; 6:104-8.

Ahmad SS, Akhtar S, Akhtar K, Naseem S, Mansoor T. Study of fine needle aspiration cytology in lymphadenopathy with special reference to Acid-fast staining in cases of tuberculosis. JK Science 2005; 7:1-4.

Nidhi P, Sapna T, Shalini M, Kumud G. FNAC in tuberculous lymphadenitis. Experience from a tertiary level referral centre. Indian J Tub 2011; 58:102-7.

Patra AK, Nanda BK, Mahapatra BK, Panda AK. Diagnosis of lymphadenopathy by fine needle aspiration cytology. Indian J Pathol Microbiol 1983; 26:273-8.

Hirachand S, Lakhey M, Akhter J, Thapa B. Evaluation of fine needle aspiration cytology of lymph nodes in Kathmandu Medical College Teaching Hospital. Kathmandu Univ Med J 2009; 7:139-42.

Maharajan M, Hiranchans S, Kafle PK, Bista M, Shresta S, Toran KC, et al. Incidence of TB in enlarged neck nodes, our experience. Kathmandu Univ Med J 2009; 7:54-8.

Bermejo A, Veeken H, Berra A. Tuberculosis incidence in developing countries with high prevalence of HIV infection. AIDS 1992; 6:1203-6.

Fatima S, Arshad S, Ahmed Z, Hasan SH. Spectrum of cytological findings in patients with neck lymphadenopathy-experience in a tertiary care hospital in Pakistan. Asian Pac J Cancer Prev 2011; 12:1873-5.

Al-Sohaibani MO. Cervical lymphadenopathy in the eastern province of Saudi Arabia. East Afr Med J 1996; 73:533-7.

Lin MH, Kuo TT. Specificity of the histopathological triad for the diagnosis of toxoplasmic lymphadenitis: polymerase chain reaction study. Pathol Int 2001; 51: 619-23.

McCabe RE, Brooks RG, Dorfman RF, Remington JS. Clinical spectrum in 107 cases of toxoplasmic lymphadenopathy. Rev Infect Dis 1987; 9:754-74.

Long CM, Smith TL, Loehr TA, Komorowski RA, Toohill RJ. Sinonasal disease in patients with sarcoidosis. Am J Rhinol 2001; 15:211-5.


Refbacks

  • There are currently no refbacks.


Copyright (c)



© 2011 Gomal Journal of Medical Sciences