shazia Rashid, Rakhshan Khurshid, Uzma Faryal Amir, Sheikh Muhammad Qaisar Rashid, Bibi Hajra, Muhammad Afaq Ali


Background: Levels of vitamin D in the population have come under increasing examination; however there are only a few studies in Saudi Arabia which measure levels in the general population. The objective of the study was to measure the association between decrease in level of vitamin D and increase in BMI in males and females of Saudi population.
Material & Methods: A cross sectional study of 94 participants with age range 16-75 years in a group of Saudi Arabian people was conducted. Duration of study was six months (June to November 2014). Both male and female were comprised into four groups, group A with an age range 15-30 years, group B with age range of 31-45 years, group C with age range of 46-61 years and group D with age range of 62-75 years. Individuals who visited with complaints of musculo skeletal pain, backache and easy fatigability were included in the study. Their body weight and height were measured for BMI. Serum levels of 25-hydroxy vitamin D [25(OH)D] in relation to demographic characteristics (age, sex) and selected health risk factors (physical activity, body mass index) were examined.
Results: Overall, the mean level of serum 25(OH )D was <20 IU in 70% female and 30% male which is recognized as vitamin D deficiency. A highly significant positive correlation (P<0.001) was observed between decrease in vitamin D and increase in BMI with r value 0.812 and 0.963 in male and female respectively.
Conclusion: Vitamin D deficiency is strongly associated in young obese people of both genders.


Vitamin D; Obesity; Body Mass Index.

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Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc 2006;81:353-73.

Larose TL, Chen Y, Camargo CA Jr, Langhammer A, Romundstad P, Mai XM. Factors associated with vitamin D deficiency in a Norwegian population: the HUNT Study. JECH 2014;68:165-70.

Holick M. Vitamin D deficiency. N Engl J Med 2007;357:266-81.

Compston JE, Vedi S, Ledger JE, Webb A, Gazet JC, Pilkington TRE. Vitamin D status and bone histomorphometry in gross obesity. Am J Clin Nutr 1981;34:2359-63.

Bell NH, Epstein S, Greene A, Shary J, Oexmann MJ, Shaw S. Evidence for alteration of the vitamin D-endocrine system in obese subjects. J Clin Invest 1985;76:370-3.

Liel Y, Ulmer E, Shary J, Hollis BW, Bell NH. Low circulating vitamin D in obesity. Calcif Tissue Int 1988;43:199-201.

Erem C, Arslan C, Hacihasanoglu A, Deger O, Topbas M, Ukinc K et al. Prevalence of obesity and associated risk factors in a Turkish population (trabzon city, Turkey). Obes Res 2004;12:1117-27.

Dimitri P, Bishop N, Walsh JS, Eastell R. Obesity is a risk factor for fracture in children but is protective against fracture in adults: a paradox. Bone 2012;50:457-66.

Brown D. Seasonal variation of slipped capital femoral epiphysis in the United States. J Pediatr Orthop 2004;24:139-43.

Ardawi MS, Sibiany AM, Bakhsh TM, Qari MH, Maimani AA. High prevalence of vitamin D deficiency among healthy Saudi Arabian men: relationship to bone mineral density, parathyroid hormone, bone turnover markers, and lifestyle factors. Osteoporos Int 2012 ;23:675-86.

Roya K, Pour MH, Zadegan NS, Sadry GH, Ansari R, Alikhassy H et al. Obesity and Associated Modifiable Environmental Factors in Iranian Adolescents: Isfahan Heart Health Promotion from Childhood. Pediatr Int 2003;45:435-42.

Galal, Osman M. The Nutrition Transition in Egypt: Obesity, Under nutrition, and the Food Consumption Context 2002;p.147.

Lau SL, Gunton JE, Athayde NP, Byth K, Cheung NW. Serum 25-hydroxyvitamin D and glycated haemoglobin levels in women with gestational diabetes mellitus. Med J Aust 2011;194:334-7.

Holick MF, Binkley NC, Bischoff-Ferrari HA. Endocrine Society. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011;96:1911-30.

Brewer L, Williams D, Moore A. Current and future treatment options in osteoporosis. Eur J Clin Pharmacol 2011;67:321-31.

“BMI Classification”. Global Database on Body Mass Index. World Health Organization 2006. Retrieved July 27, 2012.

Sahay M and Sahay R. Rickets: vitamin D deficiency and dependency. Indian J Endocrinol Metab 2012;16:164-76.

Hirani V, Cumming RG, Blyth FM, Naganathan V, Le Couteur DG, Handelsman DJ. Vitamin D status among older community dwelling men living in a sunny country and associations with lifestyle factors: the Concord Health and Ageing in Men Project, Sydney, Australia.J Nutr Health Aging 2013;17:587-93.

Daly R, Gagnon C, Lu Z, Magliano D, Dunstan D, Sikaris K et al. Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: a national, population based study. Clin Endocrinol 2012;77:26-35.

BandeiraF, Griz L, Dreyer P, Eufrazino C, Bandeira C, Freese E. Vitamin D deficiency: a global perspective. ABE&M 2006;50:128-30.

Ross AC, Manson JE, Abrams SA. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 2011;96:53-8.

Hirani V, Tull K, Ali A, Mindell J. Urgent action needed to improve vitamin D status among older people in England. Age Ageing 2010;39:62-8.

Gloth FM, Gundberg CM, Hollis BH, Haddad JG, Tobin JD. Vitamin D deficiency in homebound elderly person. JAMA 1995;274:1638-6.

Heaney RP. Functional indices of vitamin D status and ramifications of vitamin D deficiency. Am J Clin Nutr 2004;80:S1706-9.

Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers and cardiovascular disease. Am J Clin Nutr 2004;80(6 Suppl):S1678-88.

Pittas AG, Dawson-Hughes B, Li T, Van Dam R, Willett WC, Manson JE et al. Vitamin D and calcium intake in relation to type 2 diabetes in women. Diabetes Care 2006;29:650-6.

Brock K, Huang W-Y, Fraser DR, Ke L, Tseng M, Stolzenberg-Solomon R et al. Low vitamin D status is associated with physical inactivity, obesity and low vitamin D intake in a large US sample of health middle-aged men and women. J Steroid Biochem Mol Biol 2010;121:462–6.

Wortsman J, Matsuka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr 20v00;72:690-3.

Jolliffe DA, Hanifa Y, Witt KD, Venton TR, Rowe M, Timms PM et al. Environmental and genetic determinants of vitamin D status among older adults in London, UK. J Steroid Biochem Mol Biol 2016;164:30-5.

Thuesen B, Husemoen L, Fenger M, Jakobsen J, Schwarz P, Toft U. Determinants of vitamin D status in a general population of Danish adults. Bone 2012;50:605-10.


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