Shehla Aman, Sher Zamir, Jamshed Khan, Sarah Yunus, Sadaf Rasheed, Usman Ullah, Fidaullah Wazir


Background: Pregnancy-induced hypertension adversely affects the development of placenta and growth of fetus. The objective of the study was to compare the weight and volume of placentae in normotensive pregnancies versus patients with pregnancy-induced hypertension.
Material & Methods: This comparative cross-sectional study was conducted in the Department of Anatomy, Gomal Medical College, D.I.Khan, from January 2014 to October 2014. Sample size was 150. Consecutive sampling technique was used. Inclusion criteria was pregnant women of all ages and parity. Grouping variable was presence of PIH with two attributes of yes and no. Research variables were placental weight in grams and placental volume in milliliters. A total of 150 placentae with the cord were collected after delivery from pregnant women, from the labour room of obstetric unit, DHQ Teaching Hospital, D.I.Khan. Structured proforma was used to record the presence or otherwise of PIH. Subjects were divided into two groups on basis of presence or absence of PIH; group A with 50 normotensive pregnant females and group B with 100 patients with PIH. Placental weight and volume were measured in terms of mean ± SD, whereas categorical variables as frequency and percentage. Students t test was used in Social Sciences Online calculator.
Results: Out of 150 patients, 50 were normotensive and 100 were having PIH. Mean weight of placentae in groups A and B were 421.40±17.90 g and 320.60 ±14.95 g respectively whereas mean volume of placentae in groups A and B were 396.10±10.40 ml and 280.50 ±10.35 ml respectively. (p<0.01).
Conclusion: The placental weight and volume is significantly less in pregnancies with PIH in comparison to pregnancies with normal blood pressure.


Placenta; Pregnancy; Hypertension; Pregnancy-Induced.

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