Fouzia Shaikh, Sabreena Abbas, Ifat Balouch, Sabreena Talpur, Sajida Yousfani, Farwa Hashmat


Background: Eclampsia is an acute obstetric emergency carrying very high maternal morbidity and mortality risk. The objective of the study was to determin the frequency and maternal outcome of eclampsia.
Material & Methods: This cross-sectional study was conducted in the Department of Obstetrics and Gynecology, unit II, Liaquat University Hospital, Jamshoro/Hydrabad. from 1st January 2015 to 31st December 2015. A sample size of 188 was selected through non-probability, consecutive technique. All patients admitted as cases of eclampsia or who develop eclamptic convulsions after admissions in hospital whether antepartum, intrapartum or postpartum were included. Patients with hypertensive disorders during pregnancy who did not develop eclamptic convulsions or patients with seizures due to epilepsy or other disorders were excluded. Demographic variables were; age, parity, antenatal care received or not and research variable was maternal outcome in terms of discharged alive or expired. Case fatality rate was calculated. Data was entered on a pre-designed proforma. Age was numeric while all others were categorical variables. Frequency and percentages were calculated for categorical variables whereas mean and standered deviation for numeric variable. Descriptive statistical analysis was done.
RESULTS: There were 4979 obstetric admissions, with 4120 deliveries. A total of 188 patients were admitted as cases of eclampsia constituting 3.78% of obstetric admissions. Mean age of patients was 23+3.10 years. One hundred and forty seven (78%) were primigravida and 41(22%) were multigravidas. Ante natal care was 43 (23%), and majority of women first time came to know about their raised blood pressure after admission. Maternal outcome was 37(20%) patients expired and 151(80%)patients survived and discharged home. Out of total of 111 maternal deaths during the study period due to complications of eclampsia mainly pulmonary edema (66%), the case fatality rate was 19.68 %.
CONCLUSION: Eclampsia is a serious, common condition associated with significant maternal morbidity and mortality. Frequency of eclampsia is common in young and primigravada having lack of ante natal care.


Eclampsia; Pathogenesis; Strategies; Genetics; Environmental; Disease.

Full Text:



Say L, Chou D, Gemmill A, Tuncalp O, Moller AB, Daniels J. Global causes of maternal death:a WHO systematic analysis. Lancet Glob Health 2014;6:323-33.

Yargawal L, Leonardi-Bee J. Male involvement and maternal health outcomes:Systematic review and meta-analysis. J Epidemiol community Health 2015;69:604-12.

Rahman S, Tohid H. The unresolved enigma of maternal and childhood mortality in Pakistan. Pakistan J Postgrad Med Inst 2014;28:233-6.

Peters RM, Flack JM. Hypertensive disorders in pregnancy. J Obstet Gynecol Neonatal Nurs 200;33:209-20.

Gillman MW. Primordial prevention of cardiovascular disease. Circulation 2015;131:599-601.

Dodd JM, Brien CO, Grivell RM. Preventing pre-eclampsia-are dietary factors the key? BMC medicine 2014;12:174-6.

Duley L, Meher S, Abalos E. Management of pre-eclampsia BMJ 2006; 332:463-8.

Salam RA, Das JK, Lasi ZS. Diagnosis and management of pre-eclampsia in community settings in low and middle income countries. J Family Med and Prim care 2015;4:501-6.

Bhore SJ. Global Goals and Global sustainability. Int J Environ Res Public Health 2016;13:991-6.

Verguet S, Nandi A, Flippi V, Bundy DA. Maternal-related deaths and impoverishment among adolescent girls in India and Niger, findings from a modelling study. BMJ 2016;6:1586-90.

Genest DS, Falcao S, Gutkowska J, Lavoie JL. Impact of exercise training on pre-eclampsia:potential preventive mechanisms. Hypertension 2012;60:1104-9.

Chaiworapongsa T, Chaemsaithong P, Korzeniewski SJ, Yeo L, Romero R. Pre-eclampsia part 2: prediction, prevention and management. Nature Reviews Nephrology 2014;103:531-40.

Scholten RR, Thijjsen DJ, Lotgering FK, Hopman MT, Spaanderman ME. Cardiovascular effects of aerobic exercise Training in formerly pre-eclamptic women and healthy parous control subjects. AJOG 2014;211:1-11.

Jido TA. Eclampsia: maternal and fetal outcome. Afr Health Sci 2012;12:148-52.

Sultana R, Bashir R, Khan B. Presentation and management outcome of eclampsia at Ayub teaching hospital, Abbottabad. J Ayub Med Coll Abbottabad 2005;17:59-62.

Qureshi SR, Zaheer , Channa SR. Eclampsia. maternal morbidity and mode of delivery in the management. The Professional Med J 2014;21:628-32.

Yakasai IA, Gaya SA. Maternal and fetal outcome in patients with eclampsia at Murtala Muhammad Specialist Hospital Kano, Nigeria. Ann Afr Med 2011;10:304-9.

Kullima AA. A 5 year review of Maternal mortality associated with eclampsia in a tertiary care institution in northern Nigeria. Ann Afr Med 2009;8:81-4.

Chabra S, Kakani A. Maternal mortality due to eclamptic and non-eclamptic hypertensive disorders. A challenge. J Obstet Gynecol 2007;27:25-9.


  • There are currently no refbacks.

© 2011 Gomal Journal of Medical Sciences