DISTRIBUTION OF ACTIVE HEPATITIS C INFECTED POPULATION BY SEX AND AGE GROUPS IN DISTRICT D.I.KHAN, PAKISTAN

Imran Ullah, Nisar Khan, Zakirullah Khan, Fahim Ullah Khan, Abdurrehman Khan, Shafaat Ur Rehman

Abstract


Background: Untreated hepatitis C virus infection is major cause of cirrhosis and hepatocellular carcinoma causing significant morbidity and mortality. Our objectives were to determine distribution of active hepatitis C infected population by sex and age groups in District D.I.Khan, Pakistan.

Materials & Methods: This cross-sectional study was conducted at District Health Office, D.I.Khan, Pakistan from 25 April 2021 to 12 May 2021. Data was collected for period from 11 February 2017 to 22 April 2021. 1062 active hepatitis C infected cases were selected from population at risk consecutively. Sex (nominal) and age groups (ordinal) were variables. Distribution was analyzed by count, percentage and confidence intervals for proportion for population. Hypotheses for distribution were substantiated by chi-square goodness-of-fit test.

Results: Out of 1062 active hepatitis C infected population, 569 (53.58%) were men & 493 (46.42%) women, and 51 (4.80%) in age group 0-20 years, 433 (40.77%) in 21-40, 476 (44.82%) in 41-60 & 102 (9.61%) in >60 years. Our distribution by sex (p<.00001) and age groups (p<.00001) was different than expected.

Conclusion: In our study, active hepatitis C infection was more common in men than women and most common in age group 41-60 years, followed by 21-40, >60 & 0-20 years. Our observed prevalence of active hepatitis C infection in men was lower than expected & in women it was higher than expected. Our observed prevalence of active hepatitis C infection in the four age groups was not similar to expected.


Keywords


Hepatitis C; Hepatitis C virus; Distribution; Prevalence; Incidence; Population; Sex; Age groups; Chi-square Goodness of fit Test; Pakistan.

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DOI: https://doi.org/10.46903/gjms/19.03.1018

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