PHYSIOLOGICAL IMPACT OF POWDERED AND WATER-SOAKED EGGPLANT IN MALE RATS: GLYCEMIA, LIPIDS, AND MINERAL BALANCE

Shaymaa Rabeea Madhkhoor; Rabab Ali Al-Mosawi

doi:10.46903/gjms/23.4.Suppl.2145

PHYSIOLOGICAL IMPACT OF POWDERED AND WATER-SOAKED EGGPLANT IN MALE RATS: GLYCEMIA, LIPIDS, AND MINERAL BALANCE

Shaymaa Rabeea Madhkhoor, Rabab Ali Al-Mosawi

Abstract

Background: Metabolic conditions, such as diabetes and high blood pressure, are considering as the main problems that face health systems around the world. Researchers strongly work to find alternative treatment options, such as herbs, to fight these health conditions. This study aimed to investigate the effects of powdered and water-soaked eggplant on glycemic status, lipid profile, and selected serum electrolytes in male rats.

Materials & Methods: This study included the recruitment of 20 male albino rats (10 for eggplant powder experiment and 10 for water-soaked eggplant experiment), each 10 animals were divided randomly and equally into treatment and control groups. The treatment groups received either powder or a suspension of eggplant powder at 0.0143gm/5ml, each male rat was given 0.5 ml of the suspension daily for 48 days by oral gavage. Control group received distilled water only by the same route and for the same amount of time. At the end of the experiment, blood samples were collected from all rats, and glucose, electrolytes (Na, K, Ca, and Cl), and lipid profile were measured.

Results: The blood glucose levels significantly (p<0.05) decreased in treatment groups. The Cl significantly (p<0.05) decreased in treatment group from the liquid application. While, K and Ca significantly (p<0.05) increased in the treatment group from the soaked powder. Lipid profile analysis showed that triglycerides and VLDL significantly (p<0.05) decreased in the treatment group from the soaked powder, while HDL and LDL significantly (p<0.05) increased in the treatment group from the liquid application. However, a significant (p<0.05) increase in the VLDL was seen in the powder experiment.

Conclusion: Eggplant powder effect by reduction in blood glucose and LDL levels, alongside an increase in beneficial minerals such as potassium and calcium. These findings suggest a potential metabolic benefit of eggplant as a dietary supplement.

Keywords

Albino; Blood Glucose; Electrolytes; Lipid Metabolism; Metabolic Syndrome; Rats; Solanum melongena.

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References

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DOI: https://doi.org/10.46903/gjms/23.4.Suppl.2145