DISTRIBUTION OF HEPATITIS B INFECTED POPULATION BY SEX AND AGE GROUPS IN DISTRICT D.I.KHAN, PAKISTAN

Imran Ullah, Nisar Khan, Farmanullah Shah, Ejaz Ahmad, Asif Saeed

Abstract


Background: Significant morbidity and mortality is caused by untreated hepatitis B virus infection through cirrhosis and hepatocellular carcinoma. The objectives of our study were to determine distribution of hepatitis B infected population by sex and age groups in District D.I.Khan, Pakistan.

Materials & Methods: This cross-sectional study was done at District Health Office, D.I.Khan, Pakistan from January 30, 2021 to February 15, 2021. Data was collected for period from March 14, 2013 to January 28, 2021 for 2368 hepatitis B infected cases from population at risk consecutively. Sex and age groups were demographic variables. Data type was nominal for sex and ordinal for age groups. Distribution was analyzed by count, percentage and confidence intervals for proportion for population. Hypotheses for distribution were substantiated by chi-square goodness-of-fit test.

Results: Out of 2368 hepatitis B infected population, 1670 (70.52%) were men & 698(29.48%) women, and 562 (23.73%) were in age group 0-20 years, 1266 (53.46%) in 21-40 years, 462 (19.51%) in 41-60 years &78 (3.30%) in >60 years. Our distribution by sex (p<.00001) and age groups (p<.00001) were different than expected respectively.

Conclusion: In our study, hepatitis B infection was more common in men than women and most common in age group 21-40 years, followed by 0-20 years, 41-60 years and >60 years. Our observed prevalence of hepatitis B infection in men was higher than expected & in women it was lower than expected. Our observed prevalence in the four age groups was not similar to expected.


Keywords


Distribution; Population; Hepatitis B; Hepatitis B Virus; Sex; Age Groups; Chi-square Goodness of fit Test; Pakistan.

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References


Key data at a glance. In: Global progress report on HIV, viral hepatitis and sexually transmitted infections, 2021. Accountability for the global health sector strategies 2016-2021: actions for impact [accessed 2021 Feb 13]. Geneva: World Health Organization; 2021. Available at: http://apps.who.int/iris/

Global Hepatitis Report 2017 [accessed 2021 Feb 13]. Geneva: World Health Organization; 2017. Available at: http://apps.who.int/iris/

Badawi MM, Mohammed AA, Mohammed MS, Saeed MM, Ali EY, Khalil A. A diagnostic laboratory-based study on frequency and distribution of viral hepatitis B and C among Sudanese. Open Virol J 2017 Oct 31; 11:98-107. https://doi.org/10.2174/1874357901711010098

Soliman G, Elzalabany MS, Hassanein T, Miller FD. Mass screening for hepatitis B and C in Southern Upper Egypt. BMC Public Health 2019 Oct 22; 19(1):1326. https://doi.org/10.1186/s12889-019-7640-1

Tao J, Zhang W, Yue H, Zhu G, Wu W, Gong W, et al. Prevalence of hepatitis B virus infection in Shenzhen, China, 2015-2018. Sci Rep 2019 Sep 26; 9(1):13948. https://doi.org/10.1038/s41598-019-50173-5

Mousawee SM, Moossavi M, Bahrami A, Rasekh H, Naghizadeh MS, Abd H, Fereidouni M. The prevalence of hepatitis B, hepatitis C and human immunodeficiency viral infections among a large population of Afghans. Hepat Mon 2020 Jul 31; 20(7). https://doi.org/10.5812/hepatmon.101012

Khan F, Shams S, Qureshi ID, Israr M, Khan H, Sarwar MT. Hepatitis B virus infection among different sex and age groups in Pakistani Punjab. Virol J 2011 May 13; 8:225. https://doi.org/10.1186/1743-422X-8-225

Ullah Q, Khan K, Saeed K. Prevalence of hepatitis C and B in MURCY Hospital Peshawar, KP, Pakistan. J Entomol Zoo Studies 2017:1081-4.

Khan MA, Waqar M, Rehman Z, Idrees M, Wasim M, Asghar A, et al. Hepatitis B virus (HBV) a severe health problem in Mardan, Khyber Pakhtunkhwa: A molecular based study. Bio Sci Rev 2019 Feb 14;1(1):25-32. https://doi.org/10.32350/BSR.0101.03

Ullah N, Khan I, Kakakhel MA, Xi L, Bai Y, Kalra BS, et al. Serological prevalence of hepatitis B virus (HBV) in Mardan district, Khyber Pakhtunkhwa, Pakistan. Braz J Biol 2021 Jul 14; 82:e245813. https://doi.org/10.1590/1519-6984.245813

Raosoft® sample size calculator [internet]. Seattle, WA, USA: Raosoft Inc.; 2004. [accessed 2021 Feb 13]. Available at: http://www. raosoft.com/samplesize.html

Statistics Kingdom. Proportion confidence interval calculator [internet]. Statistics Kingdom; Melbourne, Australia 2007. [accessed 2021 Feb 13]. Available at: http://www.statskingdom.com/41_proportion_confidence_interval.html

Zar JH. Biostatistical Analysis. 5th ed. New York: Prentice-Hall, Inc.

Daniel WW. Biostatistics: A Foundation for Analysis in the Health Sciences. 7th ed. Singapore: John Wily; 2005.

Social Science Statistics. Statistical Tests Calculators [Internet]. [accessed 2021 Feb 13]. Available at: https://www.socscistatistics.com/tests/goodnessoffit/default2.aspx

Ghori MR, Khan H, Marwat M. Distribution of non-malignant hematological disorders by sex, age groups and type of disease based on bone marrow aspiration in population of Khyber Pakhtunkhwa, Pakistan. Gomal J Med Sci 2019 Apr-Jun; 17(2):29-36. https://doi.org/10.46903/gjms/17.02.1926

Ain N, Khan S, Marwat M, Khan N, Ahmad I, Ramzan F, et al. Frequency, distribution and determinants of hypertension in adult stroke population of D.I.Khan Division, Pakistan. Gomal J Med Sci 2019 Jul-Sep;17(3):81-9. https://doi.org/10.46903/gjms/17.03.2076

Akhtar A, Ali SM, Naqi SA, Aziz T, Shinwari W, Shah SFH. Efficacy of acetic acid versus ciprofloxacin ear drops in achieving dry ears in chronic suppurative otitis media in adult population of Islamabad, Pakistan: a non-randomized control trial. Gomal J Med Sci 2019 Jul-Sep;17(3):90-4. https://doi.org/10.46903/gjms/17.03.2007

Marwat M, Ahmad I, Ashiq F, Ali S, Zamir S, Rehman MU, et al. Frequency, distribution and determinants of diabetes mellitus in adult acute coronary syndrome population of D.I.Khan Division, Pakistan. Gomal J Med Sci 2019 Oct-Dec;17(4):131-43. https://doi.org/10.46903/gjms/17.04.2106




DOI: https://doi.org/10.46903/gjms/19.02.1017

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Copyright (c) 2021. Imran Ullah1, Nisar Khan2, Farmanullah Shah3, Ejaz Ahmad4, Asif Saeed

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